((2^8*5^-5*19^0)^-2)*(5^-2/2^3)^3*2^28 is what I believe the expression is supposed to read. -^ doesn't make sense but ^- does, so I made the relevant changes.
First, take together the numbers with exponents: 2^((8*-2)-(3*3)+28)=2^(-16-9+28)=2^3=8;
5^((-5)*(-2)+(-2*3)=5^(10-6)=5^4=625; 19^0=1.
Note that the exponents applied to the contents of the brackets act as multipliers on the exponents inside the brackets.
Now, we multiply these simplified terms together: 8*625*1=5000.